Research Abstracts Online
2008 - March 2009
University of Minnesota Twin Cities
Department of Laboratory Medicine and Pathology
PI: Henry H. Balfour, Jr.
Risk Factors for the Severity of Infectious Mononucleosis due to Primary Epstein-Barr Virus Infection in University Students (Mono 5)
Infectious mononucleosis is the result of primary Epstein-Barr Virus (EBV) infection in adolescents and young adults from resource-rich areas of the globe. Because these researchers have access to a large population of undergraduate University of Minnesota students, they are in an ideal position to investigate this characteristic manifestation of primary EBV infection. By defining risk factors for the severity of infectious mononucleosis, they might gain insight into the pathogenesis of life-threatening EBV diseases in both the normal and immunocompromised host.
These researchers are beginning a four-year clinical and laboratory study of EBV-seronegative undergraduate university students. This should allow them to define host, viral, and epidemiologic risk factors for severity of infectious mononucleosis due to primary EBV infection. The researchers are using the SDML and SDVL to aid in their analyses.
Tony Thomas, Research Associate