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Research Abstracts Online
January 2008 - March 2009

University of Minnesota Twin Cities
Institute of Technology
Department of Biomedical Engineering

PI: Victor H. Barocas, Fellow

Computational Biomechanics and Biotransport

The Barocas group uses finite-element methods to explore biomechanical and biotransport phenomena in the eye and in bioengineering tissues. Their work focuses on answering questions about the shape of the iris under various conditions and how different diseases of the iris contour evolve. They are specifically interested in angle closure glaucoma and pigmentary glaucoma, in which the iris deforms pathologically. They also work on the materials science of bioartificial tissues: how do the underlying structure and composition of an artificial tissue determine its macroscopic mechanical properties? This question is explored by means of a multiscale model, allowing the researchers to change the microstructure explicitly and locally, and then to simulate the macroscopic mechanics of the tissue. These researchers have also investigated the design of bioartificial heart valves, using fluid-solid-interaction models to predict the performance of the valve in vivo and to help guide heart-valve design.

Group Members

Rouzbeh Amini, Graduate Student
Ram Balachandran, Graduate Student
Hossam Elkhalil, Graduate Student
Faisal Hadi, Graduate Student
Sara Jouzdani, Graduate Student
Victor Lai, Graduate Student
Alex H. Lang, Supercomputing Institute Undergraduate Intern
Kunlun Liu, Research Associate
Cordelia McGehee, Undergraduate Student
Ramesh Raghupathy, Graduate Student
Edward A. Sander, Research Associate
Triantafyllos Stylianopoulos, Graduate Student
Masano Sugiyama, Graduate Student
Michael Swickrath, Research Associate
Julie Whitcomb, Graduate Student