University of Minnesota
University Relations
http://www.umn.edu/urelate
612-624-6868

Minnesota Supercomputing Institute


Log out of MyMSI

Research Abstracts Online
January 2008 - March 2009

University of Minnesota Duluth
Medical School Duluth
Department of Biochemistry and Molecular Biology

PI: Jean F. Regal
Co-PI: Ronald R. Regal
Co-PI: Mark S. Rutherford

Differential Allergen Sensitivity in Asthma of Young and Adult Animals

The objective of this research is to determine if young and adult animals differ in their sensitivity to allergens, both in the induction phase of asthma as well as in elicitation of the asthma symptoms. Besides examining pulmonary function and inflammation in the lung, this project examines gene expression in the lungs of both young and adult mammals to determine if differences can be identified in the mechanism of asthma depending on age and gender. Molecular differences discovered in different asthma phenotypes may provide information regarding appropriate therapy for the disease depending on the age and gender of the individual. The researchers use the resources of the CGL to assist in the analysis of the gene expression data.

Group Member

Amy Greene, Research Associate