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Research Abstracts Online
January 2008 - March 2009

University of Minnesota Twin Cities
Medical School
Department of Medicine

PI: Yoav Segal

Genetics of Familial Kidney Diseases

This project seeks to answer the general question of how DNA sequence changes (mutations) shed light on kidney function in health and disease. The research covers families and mouse models with several forms of genetic kidney disease, including Alport syndrome, thin basement membrane nephropathy, familial autoimmune kidney diseases, and medullary cystic kidney disease. The project uses resources at the CGL.