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Research Abstracts Online
January 2008 - March 2009

University of Minnesota Twin Cities
Medical School
Department of Medicine

PI: Keith M. Skubitz

Identification and Validation of miRNA Signature Profiles as Biomarkers for Colon Cancer Progression

The major goal of this project is to test the hypothesis that miRNAs are critical factors modulating the pathogenesis of colorectal carcinoma and can be used as potential biomarkers. miRNA profiles are identified and correlated with colon cancer progression and overall survival. Additionally, the researchers are determining the functional roles of the identified miRNAs in regulating the colon cancer phenotype.

Group Members

Pedro Barralho, Graduate Student
Rui E. Castro, Visiting Researcher
Chang-won Park, Research Associate
Jianhui Zhu, Research Associate