Research Abstracts Online
January 2009 - March 2010
University of Minnesota Twin Cities
School of Dentistry
of Diagnostic and Biological Sciences
PI: Sven-Ulrik Gorr
Sjögren's Syndrome Knowledge Base
The Sjögren’s Syndrome Knowledge Base (SSKB) is a resource for Sjögren’s syndrome research. The foundation for SSKB is a database of genes and proteins associated with Sjögren’s syndrome extracted from PubMed.
The initial search in 2007 resulted in a selection of 7,733 abstracts and 1,293 potential genes/proteins. The abstracts were manually evaluated to remove duplicates and false-positives, resulting in a preliminary database of about 900 protein names and associated genes. In the case of older publications, where gene names were not readily identifiable, gene names were assigned based on in depth evaluation of the protein name context and available gene data in public databases, including Entrez and Uniprot. The data is continually updated and manually annotated to include new publications and data relating to the genes in the SSKB.
Jane Franklin, Staff