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Research Abstracts Online
January 2009 - March 2010

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University of Minnesota Twin Cities
College of Pharmacy
Department of Experimental and Clinical Pharmacology

PI: Jatinder Lamba

Pharmacogenomics of Nucleoside Analogs

This research is focused on identifying and studying the genetic variations within the key candidate genes in the pharmacokinetic and pharmacodynamic pathways of different anticancer nucleoside analogs, such as cytarabine, gemcitabine, and clofarabine. The researchers also perform genome-wide studies to identify predictors of drug response and toxicity. They are using the BSCL and the CGL.

Group Members

Tanya Feldberg, Staff
Michael Hart, Graduate Student
Amit Kumar Mitra, Research Associate
Leslie Smith, Graduate Student