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Research Abstracts Online
January 2009 - March 2010

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University of Minnesota Twin Cities
College of Biological Sciences
College of Food, Agricultural, and Natural Resource Sciences
Department of Plant Biology

PI: Nathan M. Springer, Associate Fellow

Investigating the Sources and Consequences of Intraspecific Variation for Gene Expression in Maize

These researchers are working to understand the genetic and epigenetic sources of variation in gene expression within different inbred lines of maize. They are using a combination of microarray and allele-specific profiling to document instances of varied gene expression. By analyzing these data, they can begin to ascribe modes of regulatory variation to each gene. In particular, they are interested in how the variation combines in hybrid offspring. Hybrid maize exhibits substantial heterosis such that the hybrid is better than either parent. The group is studying how the gene expression patterns of the hybrid compare to either parent. In addition, they are doing work with comparative genome hybridizations to assess structural variation among maize inbred lines.

Group Members

Candida B. Cabral, Graduate Student
Steven Eichten, Graduate Student
Irina Makarevitch, Research Associate
Summer St. Pierre, Graduate Student
Ruth Swanson-Wagner, Research Associate