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January 2009 - March 2010

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University of Minnesota Twin Cities
Medical School
Stem Cell Institute

PI: Catherine M. Verfaillie

Transcriptome Analysis of Stem Cells

Stem cells can self-renew and differentiate. The most potent stem cell is the embryonic stem cell (ESC), which is pluripotent (can differentiate into any adult cell), whereas tissue-specific stem cells are multipotent (can only differentiate into a single family of cells). In addition, stem cells have now been isolated from adult tissues with more pluripotent characteristics. These researchers use MSI resources to profile stem cells from postnatal tissues, such as neural stem cells, hematopoietic stem cells, and mesenchymal stem cells, as well as ESC and more pluripotent adult stem cells, such as multipotent adult progenitor cells, to determine characteristics of pluripotency and multipotency.

Group Members

Fernando Ulloa Montoya, Collaborator
Jeff Ross, Collaborator
Abhishek Sohni, Graduate Student
Kartik Subramanian, Graduate Student