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Research Abstracts Online
January 2010 - March 2011

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University of Minnesota Twin Cities
Medical School
Department of Medicine

PI: Peter B. Bitterman, Associate Fellow

Translational Control of Idiopathic Pulmonary Fibrosis and Cancer

These researchers use genome-wide methods to model translational control in several major diseases, including fibrosis and lung and breast cancer. They perform resource-intense discovery of translation control mechanisms and use these to model translational deregulation. There is substantial support for an important role for translational deregulation in fibrosis and cancer, so understanding the mechanisms may lead to new therapeutic approaches.

Group Members

Ola Larsson, McGill University, Montreal, Quebec, Canada
Karen A. Smith, Research Associate