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Research Abstracts Online
January 2010 - March 2011

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University of Minnesota Twin Citites
Medical School
Department of Radiology

PI: Bruce E. Hammer

NMR Metabolomics of Osteoblasts

This research utilizes a single cell line, MC3T3 osteoblastic cells. These cells grow in well-defined chemical and physical environments and thus do not exhibit the complications typical to biofluid 1H NMR metabolomic studies. Prior studies of gravitational effects on osteoblastic cell systems focused on gene response and changes in cell differentiation. However, there are no baseline measurements of osteoblast metabolomics. This metabolomic study is discovery-driven toward finding biomarkers and sample classification at this stage of investigation.

Group Members

Hee Eun Kim, Undergraduate Student
Sam Stein, Staff