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Research Abstracts Online
January 2010 - March 2011

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University of Minnesota Twin Cities
College of Biological Sciences
College of Food, Agricultural, and Natural Resource Sciences
Department of Plant Biology

PI: Igor Libourel

Metabolic Pathway Reconstruction and Flux Analysis

These researchers are reconstructing genome-scale metabolic networks of the two annotated Ostreococcus species O. tauri and O. lucimarinus. Draft pathways are constructed from the Kyoto database and will be iteratively refined using gap analysis. The researchers are taking, and creating tools for, an algorithm-based approach to network reconstruction. This will allow them to quickly update networks to revisions in genome annotation. In addition, this generic network reconstruction approach is less biased by human curation and developed methods are cross-species applicable.

Group Members

Eli Krumholz, Undergraduate Student
Dominc Mandy, Undergraduate Student
Seijin Park, Graduate Student
Aditi Srivastava, Graduate Student
Hong Yang, Research Associate