Research Abstracts Online
January 2010 - March 2011
University of Minnesota Twin Cities
of Physical Medicine and Rehabilitation
PI: Robert P. Patterson, Associate Fellow
Modeling of Electric Potentials in Human Thorax
This project investigates various electrical measurements in the body. Three-dimensional models of the human thorax are generated from magnetic resonance images. These images are segmented and all tissues are assigned a corresponding electrical resistivity. Current paths through the body may then be studied by placing electrodes in the thorax model and solving the resulting forward problem. This group’s finite difference models consist of 3.8 million elements. Applications include design of implantable pacemakers and defibrillator electrode systems, impedance cardiography, body fluid and fat measurement, and electrical impedance tomography.
Current research is focused on measuring pulmonary edema using both internal pacemaker leads and external electrodes. Recently added work includes the effects of pulmonary edema on defibrillation thresholds. The new work will focus on user-friendly electrode positions for impedance measurements used in detecting pulmonary edema associated with heart failure and cardiac dynamics. The cardiac-dynamics application will help in better understanding the homodynamics occurring with cardiac rhythm problems. Another new application is modeling electrical impedance tomography algorithms to evaluate their performance in imaging the lungs.
Andres Belalcazar, Visiting Researcher
Fei Yang, Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri