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Research Abstracts Online
January 2010 - March 2011

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University of Minnesota Twin Cities
Academic Health Center
Masonic Cancer Center

PI: Lisa A. Peterson

Environmental Carcinogenesis

These researchers are interested in the chemical mechanism of carcinogenesis induced by environmental chemicals. They are characterizing the products formed when carcinogens and/or their metabolites modify important biomolecules such as DNA and proteins. They are also exploring projects in which they would use metabolomic, proteomic, and genomic software to analyze data. In addition, they want to perform exploratory molecular modeling experiments to understand how DNA repair proteins accommodate DNA adducts at their active sites. These studies will provide preliminary data required for an NIH grant to more fully explore structural issues affecting DNA repair by human variant repair proteins in a DNA sequence dependent manner.

Group Members

Dawn Errede, Graduate Student
Alyssa J. Fish, Staff
Martin Phillips, Graduate Student
Jingjing Shen, Graduate Student
Mathilde Sullivan, Research Associate
Ashley Terrell, Staff
Anna M. Urban, Graduate Student
Janel Warmka, Research Associate