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Research Abstracts Online
January 2010 - March 2011

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University of Minnesota Twin Cities
College of Pharmacy
Department of Pharmaceutics

PI: Ronald A. Siegel

Polymeric Biosensing and Drug Delivery Systems

These researchers are interested in using polymers, especially hydrogels, in biosensing and drug delivery systems. They are modeling the swelling of polymer hydrogels in the presence of physiological variables such as temperature, pH, and glucose concentration, and examining how swelling can be used to drive sensing and delivery processes. The work combines polymer physical chemistry and continuum mechanics. They utilize MSI in two ways. First, they use packages such as ORIGIN to organize, statistically analyze, and graphically display data that is gathered in the laboratory. Second, they use packages such as MATLAB, Mathematica, and COMSOL to perform Monte Carlo simulations and to fit the data to mathematical models that involve solution of algebraic, transcendental, ordinary differential, and partial differential equations.

Group Members

Keyur Desai, Undergraduate Student
Innocent S. Dlamini, Staff
Daniel J. Jung, Graduate Student
Arum Kim, Graduate Student
Isha Koonar, Graduate Student