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Research Abstracts Online
January - December 2011

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University of Minnesota Twin Cities
College of Science and Engineering
Department of Biomedical Engineering

PI: Matthew D. Johnson

Computational Modeling of Deep Brain Stimulation

Deep brain stimulation is a surgical therapy for several medication-refractory neurological disorders. This research focuses on developing new therapeutic approaches to managing neurological disorders through brain stimulation. The researchers develop computational models of brain anatomy reconstructed from subject MRI/CT, electric fields generated in brain tissue using finite element models, and neurons with membrane dynamics governed by sets of differential equations. They use imaging visualization and supercomputing resources to simulate neuronal activity during stimulation.

Group Members

Filippo Agnesi, Research Associate
Allison Connolly, Graduate Student
Steve Deyo, Undergraduate Student
Maureen Keane, Graduate Student
Karlo Malaga, Undergraduate Student
Kevin Mohsenian, Undergraduate Student
Ben Teplitzky, Graduate Student
Ramprasad Vijayagopal, Graduate Student
Joe Xiao, Graduate Student
Laura Zitella, Graduate Student