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Research Abstracts Online
January - December 2011

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University of Minnesota Rochester
Center for Learning Innovation

PI: Kelsey J. Metzger

Exploring Genetic Diversity in Human and Avian Genomic Samples

Investigating and characterizing human genetic variation can contribute to understanding of human evolution, human health, and disease. The human genes toll-like receptor 2 (TLR2), apolipoprotein E (APOE), reticulocalbin 2 (RCN2), early growth response 1 (EGR1), and 5- hydroxytryptamine (serotonin) receptor 1B (HTR1B) all have reported sequence variation that has been associated with various disease phenotypes. This research seeks to investigate and characterize variation (previously reported and novel) across 24 samples of human nuclear genomic DNA through PCR amplification, DNA sequencing, and subsequent sequence analysis. In addition, through a partnership with Quarry Hill Nature Center, avian genetic samples will be provided to this research group in order to carry out molecular sexing of samples.

Group Members

Jessica Gascoigne, Undergraduate Student
Chelsea Griffin, Undergraduate Student
Donhoa Thach, Undergraduate Student
Tanner VanLith, Undergraduate Student