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Research Abstracts Online
January - December 2011

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University of Minnesota Twin Cities
College of Science and Engineering
Department of Biomedical Engineering

PI: David J. Odde, Associate Fellow

Computational Cell Motility

These researchers simulate various cytoskeletal and signaling processes involved in cell division and growth. For example, microtubules are linear, self-assembled polymers that control intracellular organization and transport, and their assembly is a highly regulated process. The researchers use Monte Carlo simulation to test various theories about how microtubules assembly, and how the assembly is controlled in the cell. Also, they are interested in how kinase/phosphatase and GEF/GAP systems control cell motility. Specifically, they are investigating the role of spatial gradients generated by these reaction-diffusion systems.

Group Members

Benjamin L. Bangasser, Graduate Student
Brian Castle, Graduate Student
Clarence Chan, Graduate Student
Dominique Seetapun, Graduate Student
Emily S. Tubman, Graduate Student
Erkan Tuzel, Research Associate