Research Abstracts Online
January - December 2011
University of Minnesota Duluth
Medical School Duluth
of Biochemistry and Molecular Biology
PI: Jean F. Regal
Differential Gene Expression Analysis in Allergic Animal Models
The objective of this research is to examine mechanistic differences in pathways to the allergic phenotype depending on age, sex and allergic trigger. Besides examining pulmonary function and inflammation in the lung, this project examines gene expression in the lung to define differences. Molecular differences discovered in different asthma phenotypes will provide information regarding appropriate therapy for the disease depending on the age, gender, and inciting allergen.