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SegalY

Research Abstracts Online
January - December 2011

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University of Minnesota Twin Cities
Medical School
Department of Medicine

PI: Yoav Segal

Genetics of Familial Kidney Diseases

This project seeks to answer the general question of how DNA sequence changes (mutations) shed light on kidney function in health and disease. The research covers families and mouse models with several forms of genetic kidney disease, including Alport syndrome, thin basement membrane nephropathy, familial autoimmune kidney diseases, and medullary cystic kidney disease. The project uses MSI resources to store and analyze DNA sequence data.