Deep brain stimulation (DBS) is a surgical therapy used to treat a number of neurological disorders, including Parkinson's disease, dystonia, and essential tremor. DBS therapy involves placing small electrodes in regions of the brain that show pathological activity, and stimulating that region with pulses of electricity. Assistant Professor Matt Johnson (Biomedical Engineering) is using MSI to create simulations of neuronal activity during DBS. This image shows a simulation of a DBS lead in the pedunculopontine nucleus for treatment of Parkinson's disease. More information about Professor Johnson's research can be found in the MSI Annual Research Highlights 2011.