High Throughput Screening Data Analysis

<h3 class="red">High Throughput Screening Data Analysis</h3><p>The <a href="http://www.pharmacy.umn.edu/itdd/hts/home.html">High Throughput Screening Facility</a> supports tool and drug discovery in the <a href="http://www.pharmacy.umn.edu/itdd/home.html">Institute for Therapeutics Discovery and Development</a> in the College of Pharmacy at the University of Minnesota. The High Throughput Screening Team conducts biochemical and cell-based assay development, high throughput screening, and structure-activity relationship studies across multiple therapeutic areas. This researcher uses ActivityBase, SARview, Pipeline Pilot, and Spotfire to analyze the high throughput screening data generated in his laboratory. This involves analysis of datasets containing up to 250,000 compounds, and involves Hit Identification, analysis of the performance of the screening campaign, preliminary structure-activity relationships, and analyses of the physico-chemical properties and structural similarity of the Hits and Hit families. Additionally, analysis will be conducted&nbsp;of the screening collection of ~250,000 compounds including, for example, diversity and cluster analysis, as well as analysis of the impact of additional new screening collections on these properties of the full compound collection.</p><p>Return to this PI&#39;s <a href="https://www.msi.umn.edu/pi/274d798da40686ea3da719512d90644c/10518">main page</a>.</p>
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