Hypoxia and Tumor Angiogenesis
Faster growing tumors consume more oxygen than the available supply, which results in hypoxia. Hypoxia in cancer tissue affects the tumor microenvironment and leads to metastasis. Understanding the molecular changes in cancer cells during hypoxia can identify novel targets for drug development. This researcher is using MSI resources to help analyze genetic, epigenetic, and proteomic data to identify hypoxia regulated targets in cancer tissues.