IPA to be Discontinued
MSI will be discontinuing the license for Qiagen’s Ingenuity Pathway Analysis (IPA) software effective July 29th, 2021
Why is IPA being discontinued?
IPA has historically been a leader in pathway analysis, in part due to its proprietary pathway database for human, mouse and rat. Over the past several years, freely available pathway databases and open-source tools for pathway analysis have become available. These tools rival Qiagen’s IPA and support a broader set of study species. Several of these open-source tools have become the solutions preferred by MSI’s analysts. Going forward, MSI will be providing more explicit support for these alternative tools.
For the last several years, MSI has reviewed the software licenses we purchase to make sure our software offerings line up with our mission to provide high performance computing (HPC) services. IPA runs on Qiagen’s servers, not our HPC infrastructure, which complicates supporting and managing the software, as well as justifying it in relation to our mission. Lastly, IPA is also one of the most expensive licenses MSI purchases and the cost has been steadily increasing each year. In our current budget climate, MSI can no longer justify this expenditure when there are equally powerful free options available.
Resources and Alternatives for Pathways Analysis
While MSI will no longer offer IPA, we will continue to offer several different resources for pathway analysis. These alternatives not only support a more diverse set of species than IPA, but offer more flexibility and extensibility.
MSI will be putting together a list of resources for IPA users to aid in the transition to alternative analysis tools. Check this page regularly for the most recent developments and updates.
- Table of MSI recommended alternatives to IPA: A pathway analysis page listing alternative pathway analysis tools, including web-browser based tools and R packages to identify enriched pathways and upstream regulators
- Gallery of images of examples of IPA Alternatives (use this page in conjunction with the IPA Alternatives Table)
- Instructions for exporting data from IPA
- RNA-sequencing analysis tutorial - March 25, 2021 (Pathway analysis segment begins at time 1:35:43)
As always, you can email the MSI Helpdesk at email@example.com if you have any questions.