As a toxicology research laboratory, this group is primarily focused on the mechanisms by which foreign chemicals (specifically anti-cancer drugs and perfluorinated chemical pollutants) interfere with mitochondrial metabolism and genetics/epigenetics to beget various metabolic diseases. Some of these research projects have the potential for translation into novel strategies for enhancing cancer chemotherapeutics. In order to further the genetics/epigenetics portions of this research, the researchers are sequencing mitochondrial DNA. They are using the program Sequencher (the industry standard software for DNA sequence analysis), available through MSI for investigations into the genetic contributions to metabolic disease.
Return to this PI's main page.