Modeling Polymer Structure and Dynamics
The Dorfman group focuses on understanding the structure and dynamics of polymers, in particular DNA, across a range of length and time scales through a combination of modeling and experiments. On the engineering side, understanding the dynamics of DNA has many important applications in genomics. On the scientific side, DNA serves as a model system for investigating the basic physical properties of semiflexible polymers. The researchers are also working on block copolymer phase behavior in collaboration with Regents Professor Frank Bates, and in the next year they will start a project in collaboration with Associate Professor Dave Morse in the block polymer area. The group uses a range of simulation techniques, including Monte Carlo methods, Pruned-Enriched Rosenbluth Methods, and Brownian dynamics, to accurately predict the ensemble-averaged behavior required for specific applications.
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