Molecular Genetic Variations in Human and Avian Genomics
Investigating and characterizing human genetic variation can contribute to understanding of human evolution, human health, and disease. The human genes toll-like receptor 2 (TLR2), apolipoprotein E (APOE), reticulocalbin 2 (RCN2), early growth response 1 (EGR1), and 5- hydroxytryptamine (serotonin) receptor 1B (HTR1B) all have reported sequence variation that has been associated with various disease phenotypes. This research seeks to investigate and characterize variation (previously reported and novel) across 24 samples of human nuclear genomic DNA through PCR amplification, DNA sequencing, and subsequent sequence analysis. In addition, Saw-whet owl sequences will be used for molecular sexing of individuals. Saw-whet owls are sexually cryptic and cannot be reliably sexed using standard morphologic field metrics.
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