Tolerance in organ transplantation


Tolerance in Organ Transplantation

This project uses immune modulatory strategies to generate tolerance in transplantation. By using cellular, biologic, and pharmaceutical treatments the researchers are seeking to allow transplantation without the need for immunosuppression. This project mainly focuses on the use of suppressive regulator T cells (Treg) and blockade of co-stimulatory molecules that are required for T cell recognition of donor antigens.


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