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The University of Minnesota Biocatalysis and Biodegradation Database
The University of Minnesota Biocatalysis/Biodegradation Database
These researchers have developed several databases and tools that are housed on MSI servers. The University of Minnesota Biocatalysis and Biodegradation Database (UM-BBD) contains information on microbial biocatalytic reactions and biodegradation pathways for primarily xenobiotic, chemical compounds. The goal of the UM-BBD is to provide information on microbial enzyme-catalyzed reactions that are important for biotechnology. Its Pathway Prediction System (PPS) predicts microbial catabolic reactions using substructure searching, a rule-base, and atom-to-atom mapping. The system can recognize organic functional groups found in a compound and predict transformations based on biotransformation rules. The biotransformation rules are based on reactions found in the UM-BBD or in the scientific literature.