Carolina Sandoval Garcia

Medical School
Twin Cities
Project Title: 
Structural and Functional Imaging Connectivity in Children With Neonatal Brain Injury

This group's main hypothesis revolves around whether connectome type imaging of children with brain injury due to intraventricular hemorrhage of prematurity or other hydrocephalus etiologies can help predict the severity of neurocognitive impairment and clinical outcomes, and inform decisions regarding timing of treatment. They are exploring if structural/functional connectivity serves as an imaging biomarker to predict the severity of neurocognitive developmental outcomes and better informs timing of surgical intervention in patients with brain injury from intraventricular hemorrhage and/or hydrocephalus of other etiologies. They hope to characterize structural and functional MRI abnormalities of the brain in premature or term infants with these types of brain injuries and study clinical and neurocognitive outcomes at diagnosis and at set intervals: six months, one year, two years, and five years after presentation consistent with the current clinical follow up workflow for NICU patients as well as pre- and post-surgical treatment of hydrocephalus when required.

Project Investigators

Kristin Frenn
Julia Moser
Isabela Pena Pino
Carolina Sandoval Garcia
Kimberly Weldon
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