Lab Medicine & Pathology
Signal Transduction and Lymphocyte Development and Their Roles in Leukemia
These researchers are using MSI for three projects in their lab:
- Study of the effects of a transcription factor called STAT5b in B cells and T cells. STAT5b is associated with the development of acute lymphoblastic leukemia (ALL).
- Study of regulatory T cells, or Tregs, and how they develop. Tregs are focused on high-affinity self-antigens like insulin and in that capacity help to prevent autoimmune reactions like diabetes.
- Cancer immunotherapy, a focus that bridges the two described above. The team is tracking how the immune system responds to tumor antigens in leukemia.
Dr. Juan Abrahante - Llorens
Professor Michael Farrar
Lynn Heltemes Harris PhD
Dr. Christy Henzler
Ham Ching Lam PhD
Dr. Aaron Sarver
Kevin Silverstein PhD