Professor Michael Farrar

Lab Medicine & Pathology
Medical School
Twin Cities
Project Title: 
Signal Transduction and Lymphocyte Development and Their Roles in Leukemia

These researchers are using MSI for three projects in their lab:

  • Study of the effects of a transcription factor called STAT5b in B cells and T cells. STAT5b is associated with the development of acute lymphoblastic leukemia (ALL).
  • Study of regulatory T cells, or Tregs, and how they develop. Tregs are focused on high-affinity self-antigens like insulin and in that capacity help to prevent autoimmune reactions like diabetes.
  • Cancer immunotherapy, a focus that bridges the two described above. The team is tracking how the immune system responds to tumor antigens in leukemia.

Research by this group was featured on the MSI website in August 2020: Improving Treatments for Breast Cancer.

Project Investigators

Dr. Juan Abrahante - Llorens
Natalie David
Professor Michael Farrar
Lynn Heltemes Harris PhD
Dr. Christy Henzler
Todd Knutson
Ham Ching Lam PhD
Rebecca LaRue
Robin Lee
Sarah Munro
Christine O'Connor
David Owen
Dr. Aaron Sarver
Kevin Silverstein
Lucy Sjaastad
Sean Tracy
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