College of Science & Engineering
This group's research in the area of cell culture bioprocess engineering lies at the intersection of chemical engineering and biotechnology. New projects involve the synthetic biology approach to adeno-associated virus (AAV) productions in gene therapy, feeder-cell-free production of natural killer cells for immunotherapy, and process modeling of CHO cell culture for therapeutic protein production. Current research efforts emphasize employing -omics in those research projects to understand time-course cellular responses at different system levels and explore novel modeling approaches for quantitatively describing the cellular systems. The researchers heavily rely on advanced computational tools in bioinformatics, system biology, and machine learning to process and analyze the -omics data and eventually implement them to build predictive models for the targeted systems.