Professor Jonathan Marchant

Pharmacology
Medical School
Twin Cities
Project Title: 
Changes in Transcript Expression in Dugesia japonica After Treatment With Praziquantel

This work concerns a comparative RNA-seq project on a non-conventional model organism (planarian flatworm species), which lacks a genome. With collaboration from MSI's RIS staff, the researchers are mapping reads using an assembly they have made and are annotating results. They hope to complete this extended analysis with PacBio sequence reads to refine the current assembly. The significance of the project spans basic discovery in regenerative biology, definition of the mechanism of action of an unknown drug and bioinformatic resource optimization in an non-conventional model system.

Project Investigators

Dr. Juan Abrahante - Llorens
Dr. Joshua Baller
Professor Jonathan Marchant
Nawal Yahya
 
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