Pharmacology
Medical School
Twin Cities
Medical School
Twin Cities
Project Title:
Structural Modeling of Protein Kinases and Drug Complexes
This group studies the molecular mechanisms underlying allosteric regulation of protein kinases and allosteric drug targeting, using a variety of biophysical approaches including biomolecular spectroscopy, structure determination and biochemistry, and computational modeling. They use MSI resources primarily for molecular docking of inhibitors into kinase structures but may also expland their work into molecular dynamics simulations.
Project Investigators
Dr. Nicholas Levinson
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