Associate Professor Jenny Poynter

Pediatrics
Medical School
Twin Cities
Project Title: 
Molecular Epidemiology of Pediatric Germ Cell Tumors

The overarching goal of this work is to understand the molecular epidemiology of pediatric germ cell tumors (GCTs) and myeloid malignancy. This research involves comprehensively evaluating the molecular alterations in these rare tumors to discover differences across the histologic subtypes using methylation analysis, mRNA expression, genetic variation, and miRNA expression. Analytic tools such as Ingenuity Pathway Analysis (IPA) are used to identify pathways that are over-represented among the differentially expressed genes. These analyses can help uncover pathways that are important in the pathogenesis of GCTs and can also be useful for identifying new therapeutic targets.

Project Investigators

Shannon Cigan
Benjamin Cole
Mark Hiner
Aubrey Hubbard
Spencer Kelley
Thomas Kono
John Lane
Dr. Erin Marcotte
John Meredith
Dr. Lauren Mills
Patrick Monnahan
Rachel Moss
Associate Professor Nathan Pankratz
Associate Professor Jenny Poynter
Travis Rogers
Mary Stimson
Dr. Lindsay Williams
 
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