In humans, iron deficiency anemia during late fetal and early postnatal periods, affecting more than one billion people world wide, causes persistent cognitive and socio-emotional behavior dysfunction. Using animal models of early-life iron deficiency, these researchers investigate molecular mechanisms by which iron regulates neural development. One approach is to identify molecular changes at a genome-wide level using next generation sequencing and label-free proteomic technology. This approach will likely generate novel and testable hypotheses pertaining to molecular pathways that are persistently altered by early-life iron deficiency in the brain. Based on such insight, the reseachers hope to optimize a therapeutic strategy for prevention and treatment of early-life iron deficiency.