MSI PI Paul Dauenhauer (professor, Chemical Engineering and Materials Science (CEMS)) will lead the Center for Programmable Energy Catalysis, a new Energy Frontier Research Center that has received $10.6 million over the next four years from the U.S. Department of Energy. The center, which will include engineers and scientists from seven U.S. universities, will develop a reaction technology to transform how catalysts convert energy-rich molecules into chemical reactions.
MSI PIs Casim Sarkar (associate professor, Biomedical Engineering) and Samira Azarin (associate professor, Chemical Engineering and Materials Science) have developed a method to program the rate of a form of DNA editing called “site-specific recombination.” The new method will allow researchers to control the rate at which DNA is edited, which means they can control the speed at which a therapeutic cell produces a drug or therapeutic protein.
Climate change and land use are affecting the cold-water ecosystems of lakes in the Midwest. In a recent paper appearing in the journal Ecosphere, MSI PI Gretchen Hansen (assistant professor, Fisheries, Wildlife, and Conservation Biology) and colleagues used statistical models to determine the resilience of lakes to these effects, and determined the temperature and watershed conditions above which critical habitat was lost.
MSI PI Ningling Kang (associate professor, Hormel Institute) has received a five-year, $2 million grant from the National Cancer Institute. The grant will be used to study how colorectal cancer cells metastasize to the liver. When this type of cancer spreads to the liver, the five-year survival rate drops dramatically.
A recent study by MSI PI Emil Lou (professor, Medicine; Masonic Cancer Center) and colleagues has shown that the protein GLS1 seems to be associated with better outcomes in patients with ovarian cancer. Previously, GLS1 had been considered as a drug target for cancer treatments. This study indicates that GLS1 may have a protective effect.
MSI PI Nidhi Kohli (professor, Educational Psychology) and colleagues Panayiota Kendeou and Kristen McMaster have been awarded a five-year, $3.9 million grant from the Institute of Education Sciences. The grant will allow the researchers to scale up their Early Language Comprehensive Individualized Instruction (ELCII) technology. This technology provides supplemental early instruction in language comprehension skills.
On Wednesday, September 7, 2022, MSI staff will perform scheduled maintenance and upgrades to various MSI systems. During this month's scheduled maintenance period, primary storage, Mesabi, and Mangi will be unavailable some portion of the day. A global system reservation will start at 5:00 a.m. on September 7. Jobs that cannot be completed before 5:00 a.m. on September 7 will be held until after maintenance and then started once the system returns to production status. September maintenance will include: