posted October 28, 2013

The Great Lakes Consortium for Petascale Computation (GLCPC) has announced their Call for Proposals for annual allocations on the Blue Waters HPC system.

The GLCPC is a collaboration among colleges, universities, national research laboratories, and other educational institutions. It has been allocated 3.5 million node hours (equivalent to ~ 50 million core hours) annually on the Blue Waters supercomputer as part of the Blue Waters project. University of Minnesota faculty are eligible to apply.

The deadline for proposals is November 18, 2013. The review process is expected to be completed by early January 2014. The allocations will be available beginning April 1, 2014 and will expire one year after the time of the award.

Complete information about proposal requirements and application instructions can be found on the GLCPC website.


posted on October 17, 2013

MSI PI Assistant Professor Anna Tischler (Microbiology) has received a New Innovator Award from the National Institutes of Health. This award is presented to young researchers who received their terminal degree fewer than 10 years prior to the award. Professor Tischler’s proposal was called “High-throughput Identification of Mycobacterium tuberculosis Persistence Mechanisms.” She uses software available at MSI as part of her research into how M. tuberculosis avoids host immune responses.

More information can be found on the Medical School’s Health Talk blog.

posted on October 7, 2013

An MSI Principal Investigator is part of a new project to study diagnostic methods and treatments for meningitis. The University of Minnesota Medical School’s Division of Infectious Diseases and International Medicine have received a $3.2 million grant for this project. They will partner with Uganda’s Makerere University, with whom the U has been working for nearly ten years. The University’s story can be found in the People section of the University Relations website (October 2, “$3.2 million grant to diagnose/treat meningitis”).

Associate Professor Kirsten Nielsen (Microbiology, Medical School/College of Biological Sciences) is one of the collaborators on the project to study how sertraline, an antidepressant with antifungal properties, can be used to treat cryptococcal meningitis, which is caused by a fungal pathogen. Professor Nielsen uses MSI to study how the fungus Cryptococcus neoformans is able to cross the blood-brain barrier.

posted on September 30, 2013

On Wednesday 2 October 2013, from 04:00 - 15:00, MSI Staff will perform scheduled maintenance and upgrades to the network and various systems.

During this maintenance period, we will be performing the following updates:

  • Network firmware updates and modifications will be performed affecting internal and external connectivity for up to 1 hour
  • Koronis will be offline for system maintenance
  • Cascade will be unavailable (system updates)
  • MSI login nodes (including NX) will be rebooted and patched
  • Hosted websites will be unavailable (disk migration to the Panasas storage system)
  • Galaxy will be offline for system maintenance


Systems status is always available on our Status page.

Please email if you have any questions.


posted September 24, 2013

Several MSI PIs have been awarded patents over recent months. These PIs are among a large number of University of Minnesota faculty receiving patents, as shown in the OVPR Research blog’s story, “Recent Patents Roundup.”

Professor Michael Murtaugh (Veterinary and Biomedical Sciences), and colleague: Identifying Virally Infected and Vaccinated Organisms

Professor Murtaugh and his group use MSI resources to support their investigations of molecular mechanisms of disease resistance in swine, with particular attention on persistent viral infections and enteric immunity.

Professor Marc Hillmyer (Chemistry) and colleague: Nano-structured Polymer Composites and Process for Preparing Same

Professor Hillmyer’s group is using MSI to study poly(thienylene vinylenes), a photoactive polymer that can be used in organic photovoltaics.

Professor Carston Wagner (Medicinal Chemistry): Necleosides with Antiviral and Anticancer Activity

Professor Wagner uses MSI to model and design protein-protein interfaces.

Professor Perry Li (Mechanical Engineering): Open Accumulator for Compact Liquid Power Energy Storage

Professor Li’s group uses computational fluid dynamics (CFD) methods to develop innovative fluid power components and to develop an efficient compression/expander for compressed air energy storage. The CFD and heat-transfer studies allow the group to gain understanding of the physics and lead to improved designs.

Professor Ned Mohan (Electrical and Computer Engineering) and colleagues: Soft Switching Power Electronic Transformer

Professor Mohan’s group uses finite-element analysis programs available through MSI for their design projects.

Professor Friedrich Srienc (BioTechnology Institute): Systems and Methods of Analyzing a Particulate

Professor Srience uses MSI to run elementary mode analyses of metabolic networks. These analyses are highly computationally intensive, and the Srienc group is working with MSI staff to parallelize the algorithms.

Professor Daniel Voytas (Genetics, Cell Biology, and Development): TAL Effector-medicated DNA Modification (three patents)

Professor Voytas’s Zinc Finger Database, a web-accessible database that houses information on individual C2H2 zinc fingers and engineered zinc finger arrays, is housed at MSI.

Associate Professor Chengguo Xing (Medicinal Chemistry) and colleague: Therapeutic Compounds

Professor Xing’s group uses MSI’s computational resources and software for pathway analysis to study drug resistance in cancer, especially leukemia.