SignalP4 is software for predicting the presence and location of signal peptide cleavage sites in amino acid sequences in different organisms.

To use this program at MSI, please send a a request to and ask to be added to the SignalP4 group. The use of SignalP4 at MSI is limited to academic researchers.

To run this software interactively in a Linux environment run the commands:

module load signalp4

signalp [options] input_file

For a list of all options use the command:

signalp -h

If you encounter the error: " Command not found" or something similar, you are probably not part of the SignalP4 group. Please contact with a request to be added.
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