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Protein Adduct Biomarkers of Carcinogens
The goal of this project is to understand the reactivity of genotoxic metabolites of carcinogens in tobacco smoke and cooked meat with the blood proteins, hemoglobin and serum albumin. The researchers plan to employ PYMOL and Docking software to further their understanding of the reactivity of nucleophilic sites of these proteins with electrophiles of aromatic amines and heterocyclic aromatic amines.
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