Modeling Polymer Structure and Dynamics
The Dorfman group focuses on understanding the structure and dynamics of polymers, in particular DNA, across a range of length and time scales through a combination of modeling and experiments. On the engineering side, understanding the dynamics of DNA has many important applications in genomics. On the scientific side, DNA serves as a model system for investigating the basic physical properties of semiflexible polymers. The researchers are also working on block copolymer phase behavior, the structure of methylcelluose solutions, and polymer/particle interactions in collaboration with Regents Professor Frank Bates and Associate Professor Dave Morse. The group uses a range of simulation techniques, including Monte Carlo methods, Pruned-Enriched Rosenbluth Methods, and molecular dynamics and Brownian dynamics, to accurately predict the ensemble-averaged behavior required for specific applications.
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