Project abstract for group haase

HIV Transmission, Vaccine, and Cure

This group's research interests include: understanding the mechanisms of HIV-1 sexual transmission to women by using the rhesus macaque-SIV model and seeking the critical steps for strategies to prevent mucosal transmission; understanding the correlations of protection mediated by SIVdel-nef vaccine in order to guide the design of HIV vaccine, currently focusing on the induction of mucosal Ab responses in the female genital tract; and understanding the nature of HIV-1 latency and reservoirs in ART-treated individuals and seeking strategies to eliminate virus reservoirs to reach ultimate cure of HIV (or functional cure -- prevent virus recrudescence).

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