Project abstract for group johnsonm

Computational Modeling of Deep Brain Stimulation

Deep brain stimulation is a surgical therapy for several medication-refractory neurological disorders. This research focuses on developing new therapeutic approaches to managing neurological disorders through brain stimulation. The researchers develop computational models of brain anatomy reconstructed from subject MRI/CT, electric fields generated in brain tissue using finite element models, and neurons with membrane dynamics governed by sets of differential equations. They use imaging visualization and supercomputing resources to simulate neuronal activity during stimulation. 

A bibliography of this group’s publications acknowledging MSI is attached.