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Project abstract for group khodursk
Structure and Function of the Escherichia coli Chromosome
These researchers are investigating the effects of chromosomal DNA packing on transcription, replication, and repair. They are extracting and interpreting spatially repetitive patterns in transcriptional activity in terms of known and novel regulatory and organizational modalities. They are also formalizing the relationships between chromosomal organization and activity and bacterial susceptibility to antibiotics.