Project abstract for group manskylm

HIV and HTLV Replication

These researchers are exploring the accuracy of this process in HIV-1 replication and how it influences not only the evolution of HIV-1 variants that are resistant to anti-HIV-1 drugs, but also how it influences the development of an effective AIDS vaccine. The details behind how Gag and RNA trafficking as well as virus particle biogenesis occurs is currently being investigated via collaboration by employing highly sophisticated biophysical approaches - including fluorescence spectroscopy methodologies that have single molecule resolution as well as cryoelectron microscopy/tomography.

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