Designing Inhibitors for Low Molecular Weight Protein Tyrosine Phosphatase
The intent of this project is to design, synthesize and test compounds resembling pyridoxal 5’-phosphate (PLP). PLP is a known inhibitor of low molecular weight protein tyrosine phosphatase (LMW PTP). Inhibitors of LMW PTP may possess potential anti-cancer properties by inhibiting dephosphorylation (removal a phosphate group from a protein) of certain receptors.
A bibliography of this group’s publications is attached.
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