Project abstract for group rudneyjd

Ongoing Metaproteomic Analysis of Sucrose Effects on Oral Microcosm Biofilms

These researchers have previously reported results of a preliminary metaproteomic analysis of the effects of sucrose pulsing on oral microcosm biofilms. Shifts in expression patterns of highly abundant proteins were detectable by 1D analysis. This study extends those findings by using 2D analysis to greatly increase the number of proteins identified. The work uses the Galaxy-P platform. Present findings suggest a major role for certain species of non-mutans streptococci in sucrose-induced dysbiosis. Active removal of ammonia by assimilation may play an underappreciated role in that process.

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