Development of Antiviral and Anticancer Therapeutics
The goal of this laboratory is to apply the principles of chemical biology and medicinal chemistry to the design of new chemical- and cell-based therapies by:
- Applying chemical induced dimerization to guide the self-assembly of protein nanorings that can be used for drug delivery, tumor imaging and the targeting of immune and stem cells for tumor targeting or tissue regeneration.
- Designing therapeutic nucleotide prodrugs that can be targeted too and activated by diseased tissues.
- Uncovering the natural function of Hint proteins and applying our knowledge to the design of anticancer, antiviral drugs and new pain medications.
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