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Membrane proteins play vital roles in many cellular processes such as cell fusion, signal transduction, ion translocation, and homeostasis, among others.To link structure to function, it is necessary to understand membrane protein dynamics within their native environment.The research group of Professor Gianluigi Veglia (BMBB) uses MSI resources to develop new computational approaches to model membrane protein structures and to study their dynamics in explicit lipid membranes. This image shows an NMR structure of membrane protein phospholamban (30kDa) in lipid bilayer.
For 21 years, MSI has hosted an Undergraduate Internship Program (UIP) that provides opportunities for students to learn about supercomputing and scientific research. The 2011 MSI UIP began in June and will continue until mid-August. Nine undergraduates from around the country are working with MSI Principal Investigators on projects in a number of fields using high-performance computing environments, especially visualization and computer graphics. Interns prepare a report and give a presentation about their work. This photo was taken at the weekly lunch seminar on June 28, hosted by Assistant Professor Ryan Elliott (Aerospace Engineering and Mechanics. More information can be found on the UIP web page.
The research group of Professor Sean Garrick (MSI Fellow) at the Computational Transport Phenomena Laboratory in the Department of Mechanical Engineering uses MSI resources to model and simulate turbulent reacting flows. Jun Liu, a graduate student in the Garrick group, was a finalist in the poster competition at the recent MSI Research Exhibition. An article about his poster, which described direct numerical simulations of homogeneous metal vapor nucleation in practical flows, is planned for the Summer 2011 issue of the MSI Research Bulletin, which will be published in August 2011. The image above is taken from the poster. Pictures of all the Research Exhibition finalists can be found on the event webpage.
Fluid motion is classified as either laminar or turbulent. Flows that are smooth and ordered (laminar) may become complex and disordered (turbulent) as the flow speed increases, a process called transition to turbulence. Turbulent flow around cars, airplanes, and ships increases drag, which, in turn, forces vehicles to use more fuel and reduces the efficiency of wind-turbine blades. Assistant Professor Mihailo Jovanovic (Electrical and Computer Engineering) and his research group are developing theories and techniques for sensor-less flow control to prevent the transition to turbulence. An article about this work appears in the Spring 2011 MSI Research Bulletin. The image above shows how laminar flow around an aircraft wing or wind-turbine blade becomes complex and disordered as it moves away from the leading edge (e-fluids photo at bottom left by Miguel Visbal).
MSI researchers will present posters of their work at the 2011 MSI Research Exhibition on Monday, April 25, 1-3:30 p.m., on the fourth floor of Walter Library. The posters will be judged by a panel of MSI Principal Investigators and prizes will be awarded. Light refreshments will be served. We are very grateful to our sponsor, MathWorks, for their support of this event. More information can be found on the 2011 Research Exhibition webpage. The picture above, taken at the 2010 Research Exhibition, shows Ken Chen, a graduate student in the group of Professor Alexander Heger (Physics and Astronomy) talking about his award-winning poster with Professor Tom Jones (Astronomy, former MSI Interim Director). An article about Mr. Chen's research will appear in the Spring 2011 issue of the MSI Research Bulletin.