MACS

Software Summary

Mesabi

Default Module: 

2.1.1

Other Modules Available: 

1.4.1, 1.4.2-1, 2.1.1

Last Updated On: 

Wednesday, April 4, 2018

Itasca

Default Module: 

2.1.1

Other Modules Available: 

1.4.1, 1.4.2-1, 2.1.1

Last Updated On: 

Wednesday, April 4, 2018

Lab

Default Module: 

2.1.1

Other Versions Available: 

1.4.1, 1.4.2-1, 2.1.1

Last Updated On: 

Wednesday, April 4, 2018

Last Updated On: 

Wednesday, April 4, 2018

Support Level: 
Secondary Support
Software Access Level: 
Open Access
Software Categories: 
Genetics
Software Description
Software Description: 

MACS empirically models the length of the sequenced ChIP fragments, which tends to be shorter than sonication or library construction size estimates, and uses it to improve the spatial resolution of predicted binding sites. MACS also uses a dynamic Poisson distribution to effectively capture local biases in the genome sequence, allowing for more sensitive and robust prediction. MACS compares favorably to existing ChIP-Seq peak-finding algorithms, is publicly available open source, and can be used for ChIP-Seq with or without control samples.

Software Documentation

Software Documentation Tabs